Generic Diacetylmorphine Hydrochloride 30mg Tablets

Buy Generic Diacetylmorphine Hydrochloride 30mg Tablets

Generic Diacetylmorphine Hydrochloride 30mg Tablets

Therapeutic Class:Narcotic analgesic

Composition: containing Diacetylmorphine Hydrochloride 15mg

Description: Morphine applies an agonist effect at saturable opioid receptors in
the CNS and other tissues & acts as opioid analgesic. Morphine is an analgesic
drug used to treat acute and chronic pain. Obesity is frequently associated
with pain of various origins (e.g. arthritis, fibromyalgia, cancer), which
increases the need for analgesic drugs. Obesity changes drug pharmacokinetics,
and for certain drugs, specific modalities of prescription have been proposed
for obese patients. However, scant data are available regarding the
pharmacokinetics and pharmacodynamics of morphine in obesity. Prescription of
morphine depends on pain relief but the occurrence of respiratory adverse
effects correlates with obesity, and is not currently taken into account.
Variations in the volume of distribution, elimination half-life and oral
clearance of morphine, as well as recent advances in the respective roles of
drug-metabolizing enzymes, catechol-O-methyltransferase and the μ opioid
receptor in morphine pharmacokinetics and pharmacodynamics, may contribute to
differences between obese and non-obese patients. In addition, drug-drug
interactions may alter the disposition of morphine and its glucuronide
metabolites, which may either increase the risk of adverse effects or reduce
drug efficacy.

Indications: Severe chronic pain or pain resistant to other analgesics, in
particular pain associated with cancer.

Dosage: Adults: Recommended dosage is one tablet twice daily, at 12-hour
intervals. Elderly: As with all narcotics a reduction in dosage may be
advisable in the elderly, as appropriate.

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